The U.S. Food and Drug Administration has approved Enhertu (am-trastuzumab-deruxtecan-nxki), an intravenous infusion treatment for patients with unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-low breast cancer. HER2-low is a new subclassification within HER2-negative, describ...
Credit: Pixabay/CC0 Public Domain Not everyone who qualifies for health insurance signs up for it. Consider Medicaid, the national health insurance plan for low-income people. Across the U.S., about 14% of eligible adults and 7% of eligible children are not enrolled in Medicaid. As it happens, when adul...
If new books are lucky they enjoy a brief honeymoon of attention before ebbing away into oblivion. Not so “The Body Keeps the Score”, a publishing phenomenon that has kept selling long after it first hit the shelves in 2014. The book has spent more than 150 weeks on the New York Times best s...
Credit: Pixabay/CC0 Public Domain Sexual dysfunction is highly prevalent in women with lung cancer with most survey participants reporting little to no interest in sexual activity, according to research led by Narjust Florez (Duma), MD, associate director for the Cancer Care Equity Program at Dana-Farbe...
Credit: Pixabay/CC0 Public Domain About 53% of lung cancers in females are not attributable to smoking worldwide and a new model presented today at the IASLC World Conference on Lung Cancer may allow clinicians the ability to assess and stratify lung cancer risk in female non-smokers in China. Lanwei Gu...
Credit: Pixabay/CC0 Public Domain Researchers from Vancouver, British Columbia examine the effect of duration of past exposure to air pollution with lung cancer diagnosis. In 2013, the International Agency of Research on Cancer classified outdoor air pollution and particulate matter of 2.5 micrograms/me...
Robert Terwilliger, right, of Williamsburg, Pa., who is participating in a Lyme disease vaccine trial at the Altoona Center for Clinical Research, is injected with either the new vaccine or a placebo, by registered nurse Janae Roland, Friday, Aug. 5, 2022, in Duncansville, Pa. Lyme is a growing problem,...
Credit: Pixabay/CC0 Public Domain Synthetic cannabinoids, dangerous designer drugs known by such street names as K2, Spice or AK-47, appear to have less appeal in states that have legalized the natural form of cannabis. A Washington State University-led study found a 37% drop in poisoning reports for il...
Image of a biopsy of a diseased kidney, showing scarring and injuries to the tube-like structures. Credit: Dr Ashish Verma A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European H...
Credit: CC0 Public Domain Clinical researchers from Oxford University’s Department of Psychiatry and Oxford Health NHS Foundation Trust, together with colleagues from elsewhere, have developed guidance to help clinicians identify and treat patients at risk of suicide. The alternative approach to c...
Credit: Pixabay/CC0 Public Domain Exposure to a synthetic chemical found widely in the environment is linked to non-viral hepatocellular carcinoma, the most common type of liver cancer, according to a new study conducted by researchers from the Keck School of Medicine of USC and published in JHEP Report...
Credit: Pixabay/CC0 Public Domain Recent studies released by Dr. John Pezzuto and his team from Western New England University show “astonishing” effects of grape consumption and “remarkable” impacts on health and on lifespans. Published in the journal Foods, one study showed tha...
Credit: Pixabay/CC0 Public Domain A cohort study found that reinfection rates are low after successful hepatitis C virus (HCV) treatment in people who inject drugs (PWID), suggesting a benefit of treatment in this population. Risk for reinfection was highest in the first 24 weeks after treatment complet...
Circadian clock illustration. Credit: Shutterstock Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators. One study, published June 27, in C...
Credit: CC0 Public Domain Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, accord...
Michelle Flandez stands in her home with her two-month-old son Inti Perez, woh is diagnosed with microcephaly linked to the mosquito-borne Zika virus, in Bayamon, Puerto Rico on Dec. 16, 2016. Climate hazards such as flooding, heat waves and drought have worsened more than half of the hundreds of known...
Critical changes in the material composition of in situ forming implant formulations result in structural changes, increased payload, reduced erosion, and long-term effective drug delivery. a Schematic showing LA-RFB composition consisting of PLGA as the biodegradable polymer, DMSO or NMP as a biocompat...
Credit: Pixabay/CC0 Public Domain After news broke that the U.S. declared monkeypox to be a public health emergency, friends and family started asking me, an infectious disease epidemiologist, if monkeypox is about to begin causing widespread death and chaos. I assured them that the Aug. 4, 2022, public...
A man receives the AstraZeneca COVID-19 vaccine at Jabra Hospital in Khartoum, Sudan, Thursday, March 11, 2021. A new philanthropic project hopes to invest $100 million in up to 10 countries mostly in Africa by 2030 to support up to 200,000 community health workers. Credit: AP Photo/Marwan Ali, File A n...
There’s a direct link between low levels of vitamin D and high levels of inflammation. Credit: Rebecca Wood Inflammation is an essential part of the body’s healing process. But when it persists, it can contribute to a wide range of complex diseases including type 2 diabetes, heart disease, a...
Dr. Elizabeth Rutkowski. Credit: Augusta University Fatigue and headache were the most common symptoms reported by individuals an average of more than four months out from having COVID-19, investigators report. Muscle aches, cough, changes in smell and taste, fever, chills and nasal congestion were next...
Credit: Pixabay/CC0 Public Domain Fast food and away-from-home meal consumption is associated with increasing obesity in adults; often an unhealthy dietary behavior established in the critical time frame of young adulthood. A research article featured in the Journal of Nutrition Education and Behavior,...
The human monoclonal antibody sugemalimab is a safe and effective consolidation therapy for patients with unresectable stage III non-small cell lung cancer without disease progression after either concurrent chemoradiotherapy (cCRT) or sequential chemoradiotherapy (sCRT), according to findings presented...
A new technique can revive the cells and organs of pigs an hour after death, offering hope for future human organ donations. Scientists announced Wednesday they have restored blood flow and cell function throughout the bodies of pigs that were dead for an hour, in a breakthrough experts say could mean w...
Credit: Unsplash/CC0 Public Domain One in eight people who get coronavirus develop at least one symptom of long COVID, one of the most comprehensive studies on the condition to date suggested on Thursday. With more than half a billion coronavirus cases recorded worldwide since the start of the pandemic,...
A man walks past the Pfizer logo on the drug maker’s headquarters in New York. American drugmaker Pfizer is close to a deal to purchase Global Blood Therapeutics, which manufactures a recently approved drug against sickle-cell anemia, for $5 billion, the Wall Street Journal has reported. Pfizer, o...
Credit: Pixabay/CC0 Public Domain Over 80,000 tourists are stranded in a resort city popularly known as “China’s Hawaii” after a COVID flare-up led authorities to impose strict travel restrictions. Tourism hotspot Sanya is a city of more than a million people on the southern island of...
This image provided by the National Institute of Allergy and Infectious Diseases (NIAID) shows a colorized transmission electron micrograph of monkeypox particles (red) found within an infected cell (blue), cultured in the laboratory that was captured and color-enhanced at the NIAID Integrated Research...
To study the relationship between age and fatigue, Kessler Foundation researchers conducted a novel study using neuroimaging and self-report data. Their findings were published online on May 9, 2022, in Frontiers in Human Neuroscience. The authors are Glenn Wylie, DPhil, Amanda Pra Sisto, Helen M. Genov...
Lung CA seen on CXR. Credit: CC BY-SA 4.0 James Heilman, MD/Wikipedia A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because...
Artistic rendering of the gels encapsulating a viral vaccine. Credit: ETH Zurich / Jonathan Zawada Nearly half of all vaccines go to waste. This is due to the logistical obstacles involved in transporting them to diverse regions of the world. Most vaccines require strict temperature regulation from the...
An artist’s depiction of a T cell. Credit: NIAID During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this s...
Credit: Pixabay/CC0 Public Domain The immune boosting benefits of a tuberculosis vaccine can be seen in infants more than one year after vaccination, according to a new study. The research, led by the Murdoch Children’s Research Institute (MCRI) and published in Science Advances, has shown how the...
PET scan of a human brain with Alzheimer’s disease. Credit: public domain Mount Sinai researchers have achieved an unprecedented understanding of the genetic and molecular machinery in human microglia—immune cells that reside in the brain—that could provide valuable insights into how they contribu...
The illustration shows a portion of the receptor pGC-A, known as the extracellular domain, which protrudes from cell surfaces in the cardiovascular system. Small molecules bind with the receptor and exert subtle control over blood pressure. The new research offers the first sneak peek at the full-length...
With a new approach, the scar tissue that usually develops around medical implants has a more aligned architecture that allows drugs to pass through more easily. Credit: William Whyte et al Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes withou...
In a clinical practice guideline revision issued by the American Academy of Pediatrics and published online Aug. 5 in Pediatrics, updated recommendations are presented for the management of hyperbilirubinemia in newborn infants ≥35 weeks of gestation. In the updated guidance, Alex R. Kemper, M.D., M.P.H...
Credit: Unsplash/CC0 Public Domain As new variants of the COVID-19 virus emerge throughout the U.S., a renewed push is being made to get more Americans vaccinated. As of July 27, about 67% of Americans have been fully vaccinated for COVID, according to Centers for Disease Control and Prevention data. La...
Credit: Pixabay/CC0 Public Domain A major risk factor for diabetes, insulin resistance occurs when the cells of the body do not respond to insulin and cannot make use of the glucose (sugar) in the blood stream. The condition is known to increase the risk of cardiovascular disease and atherosclerosis, a...
Credit: CC0 Public Domain Beginning in early March 2020, military forces in the State of New York, comprising the Army National Guard, Air National Guard, Naval Militia, and State Guard, with contributions from the Army Corps of Engineers, mobilized to respond to the coronavirus pandemic. The ongoing Ne...
Credit: Pixabay/CC0 Public Domain DEAR MAYO CLINIC: Cases of COVID-19 are once again surging in parts of the U.S., and I’m hearing about different strains, such as the BA.5 and BA2.75 omicron subvariants. What do I need to do to keep my family safe, especially as I prepare to send my kids back to...
Credit: Unsplash/CC0 Public Domain Since the beginning of the COVID-19 pandemic, many pediatric patients who suffer from headaches have experienced more frequent headaches and worsening anxiety and mood, and a new study finds links to stress, decreased physical activity and increased screen time. The fi...
Designing a new generation of NIR-II D-A-D dyes by acceptor engineering strategy. a Previous NIR-II D-A-D dyes used BBT and PTQ as electron acceptors; b D-A-D NIR-II fluorophore structures of this work based on TQT acceptor. Credit: Nature Communications (2022). DOI: 10.1038/s41467-022-31521-y Near-infr...
Credit: Unsplash/CC0 Public Domain Research published from the University of Central Lancashire (UCLan), commissioned by Confliction Management Plus (CMP) and the Healthcare People Management Association (HPMA), has revealed that a lack of effective HR practice is causing challenges to the overall effec...
Registered pharmacist Sapana Patel holds a bottle of Monkeypox vaccine at a Pop-Up Monkeypox vaccination site on Wednesday, Aug. 3, 2022, in West Hollywood, Calif. Spain is struggling to curtail Europe’s leading monkeypox outbreak since the disease spread beyond Africa. The southern European natio...
This 2014 illustration made available by the U.S. Centers for Disease Control and Prevention depicts a polio virus particle. On Thursday, July 21, 2022, New York health officials reported a polio case, the first in the U.S. in nearly a decade. Credit: Sarah Poser, Meredith Boyter Newlove/CDC via AP New...
Creative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIH One in eight adults (12.7%) who are infected with SARS-CoV-2 experience long term symptoms due to COVID-19, suggests a large Dutch study published in The Lancet. The study provid...
Credit: Unsplash/CC0 Public Domain A new study at Houston Methodist evaluating the long-term effectiveness of a minimally invasive, in-office procedure could be a game changer for individuals with chronic rhinitis, an upper-respiratory condition marked by a near-constant runny nose, post-nasal drip, con...
Credit: CC0 Public Domain The polio virus was detected in more wastewater samples north of New York City, this time in a county adjacent to where an unvaccinated adult recently contracted the life-threatening disease. The polio virus was identified in wastewater collected from June and July in two locat...
Credit: Pixabay/CC0 Public Domain US President Joe Biden’s government on Thursday declared monkeypox a public health emergency, a move that should free up new funds, assist in data gathering and allow the deployment of additional personnel in the fight against the disease. The move came as nationw...
Copyright © 2021 By